I have demonstrated success and expertise in shortening the drug discovery process timeline
Led by the principal consultant, Dr. Prasad, my goal is to be an integral part of your team to accelerate the drug discovery programs using the most efficient processes including designing optimal assay funnel hit identification to preclinical candidate selection.
Having been the lead and key member of numerous drug discovery programs, I am conversant about the challenges and complexities associated with advancing programs from concept to commercialization. As an experienced leader, I am able to leverage from the lessons learned and streamline the processes and shorten the timeline to discover new chemical entities (NCEs).
Guiding clients in optimizing drug discovery and secure non- dilutive funding
Dr. Prasad is a distinguished expert in the biotechnology and pharmaceutical industries. offering a wealth of experience and knowledge across multiple domains. His expertise spans the following key areas:
Small Molecule Drug Discovery and Development
Dr. Prasad specializes in small molecule drug discovery, in his 20+ years of illustrious career he has advanced programs from target selection to IND enabling studies and contributed to the development of clinical candidates and approved therapy. His in-depth understanding of the preclinical development processes ensures that every stage, from target identification to lead optimization and preclinical development, is executed with precision and scientific rigor.
As your one stop consultant, I provide guidance and advice to both in-house team and external CROs throughout the entire process of gene to lead candidate selection. I facilitate strategizing, choosing, and designing experimental methods to ensure your drug discovery programs meet expected outcomes in a timely manner.
Enabling Entrepreneurs
As an successful entrepreneur, Dr. Prasad is passionate about mentoring the next generation of biotech and pharmaceutical innovators. He offers hands-on guidance to entrepreneurs, helping them navigate the complex processes of drug development, business strategy, and fundraising.
Dr. Prasad’s holistic approach combines scientific insight with practical business advice, empowering entrepreneurs to overcome obstacles, scale their ventures, and achieve success in a competitive industry.
Dr. Prasad’s comprehensive expertise makes him an invaluable partner for entrepreneurs and companies looking to excel in drug discovery, secure non-dilutive funding, and thrive in the entrepreneurial landscape.
Non-dilutive Funding
Navigating the financial challenges of early-stage biotech ventures is a core strength of Dr. Prasad. He excels in securing non-dilutive funding, including grants, contracts, and other non-equity financing options. His strategic approach allows companies to access essential capital without giving up ownership or control, providing the financial stability needed to advance research and development efforts. Dr. Prasad’s expertise in this area ensures that startups and established companies alike can sustain their innovation without diluting their equity.
Ways I Foster my clients Succeed
1. Small molecule drug discovery and development
Given my success in delivering new chemical entities (NCEs), across range of disease areas and targets class, I have an in-depth experience in:
- Target identification
- Cloning, expression and purification of drug targets
- Gene-to-structure – X-ray crystallography and Cryo-EM
- In silico docking, identifying novel druggable pockets in drug targets
- Customized fragment library and fragment-based drug discovery (FBDD)
- High throughput (HTS) and fragment-based screening for hit identification
- Biophysical binding assays (SPR, MST, ITC, HDX, DSF, AS-MS and NMR)
- Functional assays (Enzymatic, AlphaLisa, HTRF, FP and TR-FRET)
- Ligand bound cocrystal structures
- Iterative SAR and structure-based (SBDD) lead optimization
- Cell-based assays and Selectivity studies
- In vitro ADME
2. Enabling entrepreneurs:
As a successful entrepreneur, I help entrepreneurs succeed:
- Help setting up fully operational laboratory
- If virtual, assist with identifying and selecting CROs
- Conduct due diligence for asset in-licensing
- Help with IP and patent application
3. Non-dilutive funding:
Help prepare grant application to various funding agencies including ADDF, ALS Association, Target ALS, CDRMP, CPRIT, HDSA, MJFF, and NIH:
- Draft, review and finalize grant application
- Prepare budget, including direct and indirect costs
- Commercialization plan for NIH SBIR Phase II application
- Help with final application submission
